Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4680
rs4680
0.100 GeneticVariation BEFREE We investigated whether single nucleotide polymorphisms (SNPs) associated with neuroplasticity and activity of monoamine neurotransmitters, such as the brain-derived neurotrophic factor (BDNF, rs6265), the serotonin transporter (SLC6A4, rs25531), the tryptophan hydroxylase 1 (TPH1, rs1800532), the 5-hydroxytryptamine receptor 2A (HTR2A, rs6311, rs6313, rs7997012), and the catechol-O-methyltransferase (COMT, rs4680) genes, are associated with efficacy of transcranial direct current stimulation (tDCS) in major depression. 31721892

2019

dbSNP: rs6265
rs6265
0.100 GeneticVariation BEFREE We investigated whether single nucleotide polymorphisms (SNPs) associated with neuroplasticity and activity of monoamine neurotransmitters, such as the brain-derived neurotrophic factor (BDNF, rs6265), the serotonin transporter (SLC6A4, rs25531), the tryptophan hydroxylase 1 (TPH1, rs1800532), the 5-hydroxytryptamine receptor 2A (HTR2A, rs6311, rs6313, rs7997012), and the catechol-O-methyltransferase (COMT, rs4680) genes, are associated with efficacy of transcranial direct current stimulation (tDCS) in major depression. 31721892

2019

dbSNP: rs6313
rs6313
0.100 GeneticVariation BEFREE We investigated whether single nucleotide polymorphisms (SNPs) associated with neuroplasticity and activity of monoamine neurotransmitters, such as the brain-derived neurotrophic factor (BDNF, rs6265), the serotonin transporter (SLC6A4, rs25531), the tryptophan hydroxylase 1 (TPH1, rs1800532), the 5-hydroxytryptamine receptor 2A (HTR2A, rs6311, rs6313, rs7997012), and the catechol-O-methyltransferase (COMT, rs4680) genes, are associated with efficacy of transcranial direct current stimulation (tDCS) in major depression. 31721892

2019

dbSNP: rs6311
rs6311
0.050 GeneticVariation BEFREE We investigated whether single nucleotide polymorphisms (SNPs) associated with neuroplasticity and activity of monoamine neurotransmitters, such as the brain-derived neurotrophic factor (BDNF, rs6265), the serotonin transporter (SLC6A4, rs25531), the tryptophan hydroxylase 1 (TPH1, rs1800532), the 5-hydroxytryptamine receptor 2A (HTR2A, rs6311, rs6313, rs7997012), and the catechol-O-methyltransferase (COMT, rs4680) genes, are associated with efficacy of transcranial direct current stimulation (tDCS) in major depression. 31721892

2019

dbSNP: rs1360780
rs1360780
0.030 GeneticVariation BEFREE The purpose of the present study was to examine the possible association between the different genotypes of rs1360780 in the FKBP5 gene, and clinical symptoms in patients with unipolar depression. 31219960

2019

dbSNP: rs1800532
rs1800532
0.020 GeneticVariation BEFREE We investigated whether single nucleotide polymorphisms (SNPs) associated with neuroplasticity and activity of monoamine neurotransmitters, such as the brain-derived neurotrophic factor (BDNF, rs6265), the serotonin transporter (SLC6A4, rs25531), the tryptophan hydroxylase 1 (TPH1, rs1800532), the 5-hydroxytryptamine receptor 2A (HTR2A, rs6311, rs6313, rs7997012), and the catechol-O-methyltransferase (COMT, rs4680) genes, are associated with efficacy of transcranial direct current stimulation (tDCS) in major depression. 31721892

2019

dbSNP: rs25531
rs25531
0.020 GeneticVariation BEFREE We investigated whether single nucleotide polymorphisms (SNPs) associated with neuroplasticity and activity of monoamine neurotransmitters, such as the brain-derived neurotrophic factor (BDNF, rs6265), the serotonin transporter (SLC6A4, rs25531), the tryptophan hydroxylase 1 (TPH1, rs1800532), the 5-hydroxytryptamine receptor 2A (HTR2A, rs6311, rs6313, rs7997012), and the catechol-O-methyltransferase (COMT, rs4680) genes, are associated with efficacy of transcranial direct current stimulation (tDCS) in major depression. 31721892

2019

dbSNP: rs334558
rs334558
0.020 GeneticVariation BEFREE Notably, another promotor SNP (rs334558) of the GSK-3β gene is reportedly associated with unipolar depression, bipolar disorders, and dementia. 31742842

2019

dbSNP: rs12649507
rs12649507
0.010 GeneticVariation BEFREE BHLHB2 rs2137947 for major depressive disorder and CLOCK rs12649507 for bipolar disorder were the most significant third loci in the three-locus combination model. 31323592

2019

dbSNP: rs135745
rs135745
0.010 GeneticVariation BEFREE TIMELESS rs4630333 and CSNK1E rs135745 were significantly associated with both major depressive disorder and bipolar disorder. 31323592

2019

dbSNP: rs2137947
rs2137947
0.010 GeneticVariation BEFREE BHLHB2 rs2137947 for major depressive disorder and CLOCK rs12649507 for bipolar disorder were the most significant third loci in the three-locus combination model. 31323592

2019

dbSNP: rs4630333
rs4630333
0.010 GeneticVariation BEFREE TIMELESS rs4630333 and CSNK1E rs135745 were significantly associated with both major depressive disorder and bipolar disorder. 31323592

2019

dbSNP: rs7997012
rs7997012
0.010 GeneticVariation BEFREE We investigated whether single nucleotide polymorphisms (SNPs) associated with neuroplasticity and activity of monoamine neurotransmitters, such as the brain-derived neurotrophic factor (BDNF, rs6265), the serotonin transporter (SLC6A4, rs25531), the tryptophan hydroxylase 1 (TPH1, rs1800532), the 5-hydroxytryptamine receptor 2A (HTR2A, rs6311, rs6313, rs7997012), and the catechol-O-methyltransferase (COMT, rs4680) genes, are associated with efficacy of transcranial direct current stimulation (tDCS) in major depression. 31721892

2019

dbSNP: rs11082011
rs11082011
C 0.700 GeneticVariation GWASCAT Association of the Polygenic Scores for Personality Traits and Response to Selective Serotonin Reuptake Inhibitors in Patients with Major Depressive Disorder. 29559929

2018

dbSNP: rs11155372
rs11155372
T 0.700 GeneticVariation GWASCAT Association of the Polygenic Scores for Personality Traits and Response to Selective Serotonin Reuptake Inhibitors in Patients with Major Depressive Disorder. 29559929

2018

dbSNP: rs11591827
rs11591827
A 0.700 GeneticVariation GWASCAT Association of the Polygenic Scores for Personality Traits and Response to Selective Serotonin Reuptake Inhibitors in Patients with Major Depressive Disorder. 29559929

2018

dbSNP: rs116609693
rs116609693
T 0.700 GeneticVariation GWASCAT Beta-defensin 1, aryl hydrocarbon receptor and plasma kynurenine in major depressive disorder: metabolomics-informed genomics. 29317604

2018

dbSNP: rs11728985
rs11728985
T 0.700 GeneticVariation GWASCAT Association of the Polygenic Scores for Personality Traits and Response to Selective Serotonin Reuptake Inhibitors in Patients with Major Depressive Disorder. 29559929

2018

dbSNP: rs11990063
rs11990063
T 0.700 GeneticVariation GWASCAT Association of the Polygenic Scores for Personality Traits and Response to Selective Serotonin Reuptake Inhibitors in Patients with Major Depressive Disorder. 29559929

2018

dbSNP: rs12555870
rs12555870
G 0.700 GeneticVariation GWASCAT Association of the Polygenic Scores for Personality Traits and Response to Selective Serotonin Reuptake Inhibitors in Patients with Major Depressive Disorder. 29559929

2018

dbSNP: rs139459337
rs139459337
T 0.700 GeneticVariation GWASCAT Genome-wide association study of seasonal affective disorder. 30217971

2018

dbSNP: rs1411216
rs1411216
A 0.700 GeneticVariation GWASCAT Association of the Polygenic Scores for Personality Traits and Response to Selective Serotonin Reuptake Inhibitors in Patients with Major Depressive Disorder. 29559929

2018

dbSNP: rs144733372
rs144733372
G 0.700 GeneticVariation GWASCAT Association of the Polygenic Scores for Personality Traits and Response to Selective Serotonin Reuptake Inhibitors in Patients with Major Depressive Disorder. 29559929

2018

dbSNP: rs17211233
rs17211233
T 0.700 GeneticVariation GWASCAT Exploratory genome-wide association analysis of response to ketamine and a polygenic analysis of response to scopolamine in depression. 30552317

2018

dbSNP: rs2221540
rs2221540
G 0.700 GeneticVariation GWASCAT Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder. 30571770

2018